MSG, Obesity, and Your Health

Processed foods containing Monosodium glutamate, also known as

sodium glutamate or MSG, is the

sodium salt

of

glutamic acid

, one of the most abundant naturally occurring

non-essential

amino acids

—and

one of the most harmful things you'll find in your diet

. It's a widespread and silent killer that’s worse for your health than alcohol, nicotine and many drugs is likely lurking in your kitchen cabinets right now.

MSG has been used for more than 100 years to season food. During this period, extensive studies were conducted to elucidate the role, benefits and safety of MSG. At this point, international and national bodies for the safety of food additives consider MSG safe for human consumption as a flavor enhancer.

MSG is classified as

generally recognized as safe

(GRAS) by the European Union; and as a

food additive

by the U.S.

Food and Drug Administration

. Industrial food manufacturers market and use MSG as a flavor enhancer because it balances, blends, and rounds the total perception of other tastes.

MSG is added to thousands of the foods you and your family regularly eat, especially if you are like most Americans and eat the majority of your food as processed foods or in restaurants.

MSG is one of the worst  food additives on the market and is used in canned soups, crackers, meats, salad dressings, frozen dinners and  much more. It’s found in your local supermarket and restaurants, in your child’s school cafeteria and, amazingly, even in baby food and infant formula.

MSG is more than just a seasoning like salt and pepper, it actually enhances the flavor of foods, making processed meats and frozen dinners taste fresher and smell better, salad dressings more tasty, and canned foods less tinny.

While MSG’s benefits to the food industry are quite clear, this food additive could be slowly and silently doing major damage to your health.

The "MSG symptom complex" was originally termed the "

Chinese Restaurant Syndrome

" when Robert Ho Man Kwok anecdotally reported the symptoms he felt after an American-Chinese meal. Kwok suggested multiple reasons behind the symptoms, including alcohol from cooking with wine, the sodium content, or the MSG seasoning. But MSG became the focus and the symptoms have been associated with MSG ever since. The effect of wine or salt content was never studied. With the years, the list of

non-specific symptoms

has grown on

anecdotal

grounds. In normal conditions, humans have the ability to metabolize glutamate that has a very low

acute toxicity

. The oral lethal dose to 50% of subjects (LD50) is between 15 to 18 g/kg body weight in rats and mice respectively, five times greater than the

LD50

of salt (3 g/kg in rats). Therefore, the intake of MSG as a food additive and the natural level of glutamic acid in foods do not represent a toxicological concern in humans.

A report from the

Federation of American Societies for Experimental Biology

(FASEB) compiled in 1995 on behalf of the

United States Food and Drug Administration

(FDA) concluded that

MSG is safe when "eaten at customary levels

and although there seems to be a subgroup of apparently healthy individuals that respond with the MSG symptom complex when exposed to 3 g of MSG in the absence of food, causality by MSG has not been established because the list of MSG Symptom complex was based on testimonial reports. This report also indicates that there is no data to support the role of glutamate in chronic and debilitating illnesses. A controlled double-blind multicenter clinical trial failed to demonstrate the relationship between MSG symptom complex and the consumption of MSG in individuals that believed to react adversely against MSG. No

statistical association

has been demonstrated, there were few responses and they were inconsistent. Symptoms were not observed when MSG was given with food.

What Exactly is MSG?

You may remember when the MSG powder called “Accent” first hit the U.S. market. Well, it was many decades prior to this, in 1908, that monosodium glutamate was invented. The inventor was Kikunae Ikeda, a Japanese man who identified the natural flavor enhancing substance of seaweed.

Taking a hint from this substance, they were able to create the man-made additive MSG, and he and a partner went on to form Ajinomoto, which is now the world’s largest producer of MSG (and interestingly also a drug manufacturer).

Chemically speaking, MSG is approximately 78 percent free glutamic acid, 21 percent sodium, and up to 1 percent contaminants.

It’s a misconception that MSG is a flavor or “meat tenderizer.” In reality, MSG has very little taste at all, yet when you eat MSG, you think the food you’re eating has more protein and tastes better. It does this by tricking your tongue, using a little-known fifth basic taste: umami.

Umami is the taste of glutamate, which is a savory flavor found in many Japanese foods, bacon and also in the toxic food additive MSG. It is because of umami that foods with MSG taste heartier, more robust and generally better to a lot of people than foods without it.

The ingredient didn’t become widespread in the United States until after World War II, when the U.S. military realized Japanese rations were much tastier than the U.S. versions because of MSG.

In 1959, the U.S. Food and Drug Administration labeled MSG as “Generally Recognized as Safe” (GRAS), and it has remained that way ever since. Yet, it was a telling sign when just 10 years later a condition known as “Chinese Restaurant Syndrome” entered the medical literature, describing the numerous side effects, from numbness to heart palpitations, that people experienced after eating MSG.

Today that syndrome is more appropriately called “MSG Symptom Complex,” which the Food and Drug Administration (FDA) identifies as "short-term reactions" to MSG. More on those “reactions” to come.

Why MSG is so Dangerous

One of the best overviews of the very real dangers of MSG comes from Dr. Russell Blaylock, a board-certified neurosurgeon and author of “

Excitotoxins: The Taste that Kills

.” In it he explains that MSG is an excitotoxin, which means it overexcites your cells to the point of damage or death, causing brain damage to varying degrees—and potentially even triggering or worsening learning disabilities, Alzheimer’s disease, Parkinson’s disease, Lou Gehrig’s disease and more.

Part of the problem also is that free glutamic acid is the same neurotransmitter that your brain, nervous system, eyes, pancreas and other organs use to initiate certain processes in your body.

Even the FDA states:

“Studies have shown that the body uses glutamate, an amino acid, as a nerve impulse transmitter in the brain and that there are glutamate-responsive tissues in other parts of the body, as well. Abnormal function of glutamate receptors has been linked with certain neurological diseases, such as Alzheimer's disease and Huntington's chorea. Injections of glutamate in laboratory animals have resulted in damage to nerve cells in the brain.”

Although the FDA continues to claim that consuming MSG in food does not cause these ill effects, many other experts say otherwise. According to Dr. Blaylock, numerous glutamate receptors have been found both within your heart's electrical conduction system and the heart muscle itself. This can be damaging to your heart, and may even explain the sudden deaths sometimes seen among young athletes.

He says:

“When an excess of food-borne excitotoxins, such as MSG, hydrolyzed protein soy protein isolate and concentrate, natural flavoring, sodium caseinate and aspartate from aspartame, are consumed, these glutamate receptors are over-stimulated, producing cardiac arrhythmias.

When magnesium stores are low, as we see in athletes, the glutamate receptors are so sensitive that even low levels of these excitotoxins can result in cardiac arrhythmias and death.”

Many other adverse effects have also been linked to regular consumption of MSG, including:

  • Obesity

  • Eye damage

  • Headaches

  • Fatigue and disorientation

  • Depression

Further, even the FDA admits that “short-term reactions” known as MSG Symptom Complex can occur in certain groups of people, namely those who have eaten “large doses” of MSG or those who have asthma.

According to the FDA, MSG Symptom Complex can involve symptoms such as:

  • Numbness

  • Burning sensation

  • Tingling

  • Facial pressure or tightness

  • Chest pain or difficulty breathing

  • Headache

  • Nausea

  • Rapid heartbeat

  • Drowsiness

  • Weakness

No one knows for sure just how many people may be “sensitive” to MSG, but studies from the 1970s suggested that 25 percent to 30 percent of the U.S. population was intolerant of MSG -- at levels then found in food. Since the use of MSG has expanded dramatically since that time, it’s been estimated that up to 40 percent of the population may be impacted.

How to Determine if MSG is in Your Food

Food manufacturers are not stupid, and they’ve caught on to the fact that people like you want to avoid eating this nasty food additive. As a result, do you think they responded by removing MSG from their products? Well, a few may have, but most of them just tried to “clean” their labels. In other words, they tried to hide the fact that MSG is an ingredient.

How do they do this? By using names that you would never associate with MSG.

You see, it’s required by the FDA that food manufacturers list the ingredient “monosodium glutamate” on food labels, but they do not have to label ingredients that contain free glutamic acid, even though it’s the main component of MSG.

There are over 40 labeled ingredients that contain glutamic acid,

but you’d never know it just from their names alone. Further, in some foods glutamic acid is formed during processing and, again, food labels give you no way of knowing for sure.  

Tips for Keeping MSG Out of Your Diet

In general, if a food is processed you can assume it contains MSG (or one of its pseudo-ingredients). So if you stick to a whole, fresh foods diet, you can pretty much guarantee that you’ll avoid this toxin.

The other place where you’ll need to watch out for MSG is in restaurants. You can ask your server which menu items are MSG-free, and request that no MSG be added to your meal, but of course the only place where you can be entirely sure of what’s added to your food is in your own kitchen.

To be on the safe side, you should also know what ingredients to watch out for on packaged foods.

Here is a list of ingredients that

ALWAYS contain MSG

:

 Autolyzed Yeast

 Calcium Caseinate

Gelatin 

 Glutamate

Glutamic Acid

Hydrolyzed Protein 

 Monopotassium Glutamate

Monosodium Glutamate 

Sodium Caseinate 

 Textured Protein

Yeast Extract

Yeast Food 

 Yeast Nutrient

These ingredients OFTEN contain MSG or create MSG during processing:

 Flavors and Flavorings

Seasonings 

Natural Flavors and Flavorings 

Natural Pork Flavoring

Natural Beef Flavoring 

 Natural Chicken Flavoring

Soy Sauce 

Soy Protein Isolate 

Soy Protein 

Bouillon 

 Stock 

Broth 

Malt Extract 

Malt Flavoring 

Barley Malt 

 Anything Enzyme Modified

Carrageenan 

Maltodextrin 

Pectin 

Enzymes 

 Protease 

Corn Starch 

Citric Acid 

Powdered Milk 

Anything Protein Fortified 

Anything Ultra-Pasteurized 

So if you do eat processed foods, please remember to be on the lookout for these many hidden names for MSG.

Choosing to be MSG-Free

Making a decision to avoid MSG in your diet as much as possible is a wise choice for nearly everyone. Admittedly, it does take a bit more planning and time in the kitchen to prepare food at home, using fresh, locally grown ingredients. But knowing that your food is pure and free of toxic additives like MSG will make it well worth it.

Plus, choosing whole foods will ultimately give you better flavor and more health value than any MSG-laden processed food you could buy at your supermarket.

How MSG affects the body

Scientists in Spain have recently concluded that MSG when given to mice increase appetite by as much as 40%.  

Here's another list of

hidden MSG sources

:

Names of ingredients that always contain processed free glutamic acid:

Glutamic acid (E 620)

2

,  Glutamate (E 620)

Monosodium glutamate (E 621)

Monopotassium glutamate (E 622)

Calcium glutamate (E 623)

Monoammonium

glutamate (E 624)

Magnesium glutamate (E 625)

Natrium

glutamate

Yeast extract

Anything

“hydrolyzed”

Any

“hydrolyzed protein”

Calcium caseinate,  Sodium caseinate

Yeast food, Yeast nutrient

Autolyzed yeast

Gelatin

Textured protein

Soy protein, soy protein concentrate

Soy protein isolate

Whey protein, whey protein concentrate

Whey protein isolate

Anything

“…protein”

Vetsin

Ajinomoto

Names of ingredients that

often

contain or produce processed free glutamic acid:

Carrageenan (E 407)

Bouillon and broth

Stock

Any

“flavors” or “flavoring”

Maltodextrin

Citric acid, Citrate (E 330)

Anything

“ultra-pasteurized”

Barley malt

Pectin (E 440)

Protease

Anything

“enzyme modified”

Anything containing

“enzymes”

Malt extract

Soy sauce

Soy sauce extract

Anything

“protein fortified”

Anything

“fermented”

Seasonings

(1) Glutamic acid found

in unadulterated

protein

does not cause adverse reactions.  To cause adverse reactions, the glutamic acid must have been

processed/manufactured

or come from protein that has been fermented.

The following are ingredients suspected of containing or creating sufficient processed free glutamic acid to serve as MSG-reaction triggers in HIGHLY SENSITIVE people:

Corn starch 

Corn syrup 

Modified food starch 

Lipolyzed

butter fat 

Dextrose

Rice syrup

Brown rice syrup 

Milk powder

Reduced fat milk (skim; 1%; 2%)  

most things

low fat or no fat 

anything

Enriched

anything

Vitamin enriched

(2) E numbers are use in Europe in place of food additive names.

The following work synergistically with MSG to enhance flavor.  If they are present for flavoring, so is MSG.

Disodium 5’-guanylate (E 627)      Disodium 5’-inosinate (E-631)     Disodium 5'-ribonucleotides (E 635)

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Nicole Caldwell

Nicole Caldwell is a self-taught environmentalist, green-living savant and sustainability educator with more than a decade of professional writing experience. She is also the co-founder of Better Farm and president of betterArts. Nicole’s work has been featured in Mother Earth News, Reader’s Digest, Time Out New York, and many other publications. Her first book, Better: The Everyday Art of Sustainable Living, is due out this July through New Society Publishers.